World
Race for the first artificial embryos
“The first artificially created human embryo” – at first there was nothing more than a headline. But more backgrounds are now known. And they raise big ethical questions.
It was only a matter of time: Just a year ago, two competing research groups succeeded in creating artificial mouse embryos. Transferring this technology to human cells was the next logical step. The only question was: who would succeed first? A veritable race has broken out in biomedical research.
At a conference in Boston, American developmental biologist Magdalena Zernica-Goetz explained that she and her team had done just that: They had created a model of the human embryo from stem cells. There was no verifiable data yet, but after the media reported it, the public excitement was great.
competing teams Publish data
A few days later, a rival team from Israel uploaded such teams Results on a prepress server High: They also transferred their mouse findings into human cells and produced embryo-like structures. Other international groups followed, and eventually that too was published US team data.
Even if none of the published studies have been reviewed by independent experts, the experts are talking about a breakthrough.
Stem cells instead of fertilized egg cells
In order to create the model embryos, the researchers didn’t need an egg cell, sperm, or fertilization. Instead, they manipulated human cells in the lab so that they regressed — into so-called stem cells. A variety of cell types can then emerge from these primary cells. And: Stem cells can be induced to form an embryo in the laboratory. Or at least something that closely resembles a real 13- to 14-day-old human embryo.
Michelle Poigny describes this progress as a „radical turning point”. He is the head of the working group „Mouse Embryology” at the Max Planck Institute for Molecular Biomedicine in Münster. Because: „For the first time in research, egg cells are no longer needed to develop human embryos in the laboratory.” But is what was actually created an embryo? This is now under discussion.
Embryos are more strictly protected than stem cells
Because in Germany it is forbidden to conduct research on embryos. According to the law, an embryo is created by definition from a fertilized egg cell. So the artificial embryos would not be blocked from stem cells. So the researchers call them embryonic models, or embryo-like structures, in their publications.
But in addition to the linguistic, there are also ethical challenges related to science and society. „Are artificial embryos less protective than extra embryos resulting from fertility treatment, for example? ”
Nils Hoppe and Sarah Rutger of the Center for Ethics and Law in the Life Sciences at Hannover University pose this question in a joint statement. „We will have to reorient ourselves socially again.” The German embryo protection law does not keep pace with scientific progress, so it must be completely replaced by a new, more modern law.
The field of research in reproduction
But scientific progress also gives hope. Because there is still so much that is not known about human reproduction. And it’s surprisingly ineffective. About 60 percent of pregnancies are already lost in the first two weeks after fertilization, and pregnant women often don’t realize this.
Relatively little is known about the reasons for this. This is also due to the strict rules for searching for human fetuses. This is where artificial embryo models can be used.
I wish for Basic research
Jesse Venfleet, head of the Stem Cell Genesis Working Group at the Max Planck Institute for Molecular Cell Biology and Genetics (CBG) in Dresden, sees great potential: „The similarity in terms of cellular structure, architecture and organization is incredible.” Many important milestones in early human development will be passed.
But not all of them: „In particular, embryo-like structures don’t go through the blastocyst stage — the stage when a normal embryo implants itself in the uterus.” It is not yet known to what extent this will affect the developmental potential of the embryo-like structures, that is, whether they are capable of producing a healthy, fully formed embryo, Feinfleet says.
The embryo models presented will provide a unique opportunity to learn more about human pregnancies and why they often fail at crucial stages. „But it is important to understand both the similarities and differences between an embryo and its model.”
„Praktyk żywieniowy. Guru bekonu. Irytująco pokorny entuzjasta zombie. Uczeń totalny”.
He presses
Russia suspects a complex plan behind the attack on the Crimean bridge in 2022. Kiev confirms involvement – are more attacks planned?
KERCH – Ukraine repeatedly resorts to unconventional means in its defensive battle against Russian leader Vladimir Putin’s army – perhaps also due to a persistent ammunition shortage. next to 3D printed bombsAs with those used in Ukraine’s war last year, the Crimean Bridge is also said to have been destroyed using an explosive device, the Ukrainian online newspaper reported. Ukrainian Pravda.
The strategically important Kerch Bridge, which connects the Russian mainland to the annexed Crimean peninsula, has been attacked several times by the Ukrainian army. It is now said that an explosive attack has been detected on October 8, 2022 and reveals a complex plan. The explosive device that caused extensive damage to the bridge appears to have been hidden among several rolls of plastic wrap – and had traveled a long time ago.
Traveling for more than two months – the explosive device remained undetected by Russia
The homemade explosive device was said to have relied on solid rocket fuel, according to the Russian newspaper Kommersant Citing reported investigative materials. Even more surprising than the explosive device itself is how it got to the Qurum Bridge in the first place. Hidden among 22 pallets of polyethylene film, it is said to have initially arrived in Georgia from the Ukrainian city of Odessa. From there it was transported to Armenia, where the shipment was cleared through customs. The accompanying documents have been replaced in the meantime.
The pallets were then delivered on a truck across the Georgian-Russian border to Armavir in Russia’s Krasnodar region, Russian investigations showed. The explosive device spent the rest of the journey in a Russian truck, the driver of which is said to have known nothing about the plans.
According to Russian authorities, Ukrainian backers chose this complicated route for a very specific purpose. This was an attempt to distract attention from the actual goods – and it is clearly a successful tactic.
Ukraine waited for the right time, as an explosive device was detonated on the Crimean GPS bridge.
Russia believes Ukrainian President Volodymyr Zelensky ordered the Ukrainian secret service to carry out the attack on the Kerch Bridge, according to reports. Newsweek. He equipped the explosive device with a GPS system, causing the bomb to explode in a pre-determined section of the bridge. This information cannot currently be independently verified.
However, the attack did not fail to have its effect: using an explosive force of about 10 tons of TNT, large parts of the bridge were severely damaged. Two bridges collapsed as a result of the explosion, and 17 cargo tanker cars loaded with fuel were damaged. as Daily news It was reported that at least three people died in the explosion.
Military bloggers fear further attacks by Ukraine on the Crimean Bridge
Kiev is said to be upon request Newsweek Claims responsibility for the attack on the Kerch Bridge. It is assumed in Russia that Ukraine is planning more such measures. The Ryapar channel, which is said to be linked to the Russian Defense Ministry, expressed similar concerns on Telegram last week.
Accordingly, Ukraine used American decoy missiles to locate Russian air defense systems and radars. The channel suspects that this is preparation for another attack on the strategically important bridge. This may happen before Putin is officially inaugurated as Russian president on May 7. (prohibit)
„Praktyk żywieniowy. Guru bekonu. Irytująco pokorny entuzjasta zombie. Uczeń totalny”.
World
Conflict with China: Baerbock does not rule out the presence of a German frigate in the Taiwan Strait
Foreign Minister Annalena Baerbock does not rule out that it could be the frigate Baden-Württemberg It will also transit the Taiwan Strait on its next mission in the Pacific. The Green politician said during her visit to New Zealand that the route of the warship and supply ship would not be announced in advance. But she stressed that the „right of peaceful passage” also applies to the road Taiwan Progressing. “The same rules apply there as in all similar maritime areas in which our ships and other vessels sail.” The training mission of the two ships is carried out on this basis.
Frigate Baden-Württemberg and task force provider Frankfurt am Main They will begin a round-the-world journey next Tuesday, during which they will travel through the Panama Canal Pacific And then it also crosses the South China Sea. There was already a similar mission from August 2021 to February 2022. The frigate Bavaria It participated in maneuvers with its allies at the time, but avoided Taiwan.
Chinese threat of invasion
The Taiwan Strait can be crossed from China To be seen as a provocation. The People’s Republic claims the Democratic Republic of Taiwan as its own territory. The central government in Beijing is striving for „reunification” with the island, and has repeatedly threatened to invade it.
Despite Chinese threats, the United States, Great Britain, and France regularly maintain a military presence in the strait between Taiwan and China. Taiwan’s representative in Germany, Jhy-Wey Shieh, recently requested the frigate in an interview with the German News Agency (DPA). Baden-Württemberg You should follow this example. It was „disappointing” that this happened in the previous mission Bavaria He said that was not the case.
Meanwhile, Naval Inspector Jean-Christian Kack called for an order to purchase two more frigates for the Navy and warned of the risks of increased costs. “I think it is absolutely necessary for Germany to make this choice and order these two frigates. I agree with the Minister on this matter, because we must now invest in the fleet of the future so that we can continue to fulfill our tasks of protecting our ships. The Vice Admiral told the German news agency ( DPA: “People can guarantee this in the long run.”
Construction of the first F126 frigate began in December. A total of four new frigates are being financed, and there is an option for two more ships at a similar price. “Any delay or failure to use this option will lead to increased costs when ordering later,” Kak warned.
Foreign Minister Annalena Baerbock does not rule out that it could be the frigate Baden-Württemberg It will also transit the Taiwan Strait on its next mission in the Pacific. The Green politician said during her visit to New Zealand that the route of the warship and supply ship would not be announced in advance. But she stressed that the „right of peaceful passage” also applies to the road Taiwan Progressing. “The same rules apply there as in all similar maritime areas in which our ships and other vessels sail.” The training mission of the two ships is carried out on this basis.
„Praktyk żywieniowy. Guru bekonu. Irytująco pokorny entuzjasta zombie. Uczeń totalny”.
During the attack on the Crimean Bridge
Russia threatens „devastating retaliation”
May 3, 2024 at 10:08 pm
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The Crimean Bridge near Kerch plays an important role in the logistics of Russian forces in Ukraine. Moscow expects Ukraine to launch an attack on Putin’s majestic palace in the coming days, and threatens the consequences.
Russia warned of a „devastating retaliatory strike” if Ukraine attacks Crimea or the Crimean Bridge with Western support. Foreign Ministry spokeswoman Maria Zakharova said in Moscow at a press conference: “I would like to once again warn Washington, London and Brussels that any aggressive actions against Crimea will not only be doomed to failure, but will also be met with a devastating retaliatory strike.” In the Russian capital.
In recent days, the Ukrainian Armed Forces have been observed using several ATACMS missiles against Crimea. Zakharova said: “According to the Russian Ministry of Defense, all the missiles launched were destroyed.” She expressed doubts that the government in Kiev was planning a major attack before or on May 9. On this day, Russia celebrates the victory of the Soviet Union over Germany in World War II.
Attacks on anti-aircraft systems
The Russian Ministry of Defense announced on Tuesday that it had intercepted six ATACMS missiles over the Crimean Peninsula. However, independent media reported attacks on three military bases on the peninsula. The attacks were aimed at confronting Russian air defense systems.
The independent Internet portal Astra reported that a fire broke out during an attack on an anti-aircraft position near Simferopol. Djankoy Airport, where the helicopter regiment and anti-aircraft defense forces are based, also came under fire. According to Astra, four soldiers were injured in an attack on a military facility in the Chornomorsky region, northwest of the peninsula. The United States had announced that it would also deliver long-range ATACMS missiles to Ukraine as part of the new weapons package. In previous deliveries, its range was limited to 165 km.
The Crimean Bridge near Kerch, opened by Kremlin President Vladimir Putin in 2018, connects southern Russia to the peninsula that was annexed in violation of international law, and constitutes an important supply route for Russian associations in southern Ukraine. At the end of October 2022, an explosion stopped traffic on the bridge for several months. Marine drone and missile attacks later followed. Kiev has repeatedly stressed that it wants to liberate the peninsula.
„Praktyk żywieniowy. Guru bekonu. Irytująco pokorny entuzjasta zombie. Uczeń totalny”.
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